Chapter 8 The lymphorecticular system and bone marrow/Fig 8.41.jpg

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Bone marrow trephine biopsy in multiple myeloma. (A) Haematoxylin and eosin staining shows confluent sheets of atypical plasma cells. (B) The neoplastic plasma cells stain only for kappa light chain using immunocytochemistry and are therefore monoclonal. (C) The same population of cells is negative for lambda light chain.