Chapter 8 The lymphorecticular system and bone marrow/Fig 8.17.jpg

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(A) H&E staining of colonic biopsy. There is a lymphomatous infiltrate within the mucosa and submucosa which is composed of a diffuse infiltrate of lymphoid cells resembling centrocytes. (B) Immunocytochemistry for cyclinD1. There is nuclear expression of cyclinD1 in the neoplastic lymphoid population (not normally seen in other types of lymphoma).