Chapter 8 The lymphorecticular system and bone marrow/Fig 8.01.jpg

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Diagrammatic structure of a lymph node. Material enters the sinus network of the lymph node via the afferent lymphatics. The phagocytic cells which line the sinuses entrap the antigenic material and deliver it to antigenpresenting cells within the B- and T-cell areas. A B-cell reaction results in germinal centre formation within the cortex, which leads to the production of plasma cells and memory cells which re-circulate. T-cell reactions occur mainly within the deep paracortical areas.