Chapter 19 Infections/Fig 19.01.jpg

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Human immunodeficiency virus (HIV) infection. HIV enters the Langerhans dendritic cell, via gp120 binding to the receptors CD4 and CCR5; HIV then spreads to the T cells via the same receptors, and throughout the lymphoid system. Over time, the virus mutates and enters T cells via CD4 and CXCR4 receptors.