Chapter 17 The endocrine system/Fig 17.02.jpg

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FIGURE 17.2 Sections from a pituitary tumour in a patient with hyperprolactinaemia. (A) Immunostaining for prolactin is negative, because the tumour cells are not storing the hormone. (B) In-situ hybridization for prolactin mRNA gives a positive signal, confirming that the tumour is producing the hormone.