Chapter 12 The locomotor system/Fig 12.33.jpg

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Rheumatoid arthritis. The knee joint (A) has been opened to show the distal femur whose articular cartilage has been eroded from the periphery by haemosiderin-stained pannus. Low-power microscopy (B) demonstrates that the pannus grows over and erodes the cartilage. The synovium (C) shows a villous architecture, the fronds are densely infiltrated by chronic inflammatory cells and there is fibrinous exudate.