Chapter 12 The locomotor system/Fig 12.11.jpg

You can download this figure by right-clicking it and choosing 'Save Picture As...'

Paget’s disease of bone. (A) The active phase is characterized by numerous large osteoclasts eroding bone, followed by new bone formation by sheets of osteoblasts. The marrow is replaced by vascular fibrous tissue. (B) Repeated episodes of irregular resorption and synthesis result in a jigsaw or mosaic pattern of cement (reversal) lines.