Chapter 12 The locomotor system/Fig 12.08.jpg

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Brown tumour of hyperparathyroidism. The patient was a middle-aged woman with a past history of two malignant tumours who developed a destructive lesion of the distal humerus. Biopsy shows numerous osteoclasts among fibrous stroma and some reactive new bone formation. She was also known to have chronic renal failure. The lytic lesion rapidly filled-in following removal of an enlarged parathyroid gland.